Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy

Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical patient data. Here, male and female B6C3F1 mice wer...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Blyth, Benjamin J., Kakinuma, Shizuko, Sunaoshi, Masaaki, Amasaki, Yoshiko, Hirano-Sakairi, Shinobu, Ogawa, Kanae, Shirakami, Ayana, Shang, Yi, Tsuruoka, Chizuru, Nishimura, Mayumi, Shimada, Yoshiya
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488329/
https://ncbi.nlm.nih.gov/pubmed/26125582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130666
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