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Cofilin Drives Cell-Invasive and Metastatic Responses to TGF-β in Prostate Cancer

Cofilin (CFL) is an F-actin–severing protein required for the cytoskeleton reorganization and filopodia formation, which drives cell migration. CFL binding and severing of F-actin is controlled by Ser3 phosphorylation, but the contributions of this step to cell migration during invasion and metastas...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Collazo, Joanne, Zhu, Beibei, Larkin, Spencer, Martin, Sarah K., Pu, Hong, Horbinski, Craig, Koochekpour, Shahriar, Kyprianou, Natasha
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488067/
https://ncbi.nlm.nih.gov/pubmed/24509905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3058
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