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Reversion of epithelial-mesenchymal transition by a novel agent DZ-50 via IGF binding protein-3 in prostate cancer cells

Dysregulation of transforming growth factor-β1 (TGF-β1) and insulin-like growth factor (IGF) axis has been linked to reactive stroma dynamics in prostate cancer progression. IGF binding protein-3 (IGFBP3) induction is initiated by stroma remodeling and could represent a potential therapeutic target...

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Publicat a:Oncotarget
Autors principals: Cao, Zheng, Koochekpour, Shahriar, Strup, Stephen E., Kyprianou, Natasha
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667978/
https://ncbi.nlm.nih.gov/pubmed/29108245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19659
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