Fingerprinting the folding of a group I precursor RNA.

Evidence that folding of the Tetrahymena pre-rRNA follows a defined path and is rate-determining for splicing at physiological temperatures is presented. Structural isomers were separated by native polyacrylamide gel electrophoresis and their splicing activities were compared. GTP binding selectivel...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Emerick, V L, Woodson, S A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9675
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