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Fingerprinting the folding of a group I precursor RNA.

Evidence that folding of the Tetrahymena pre-rRNA follows a defined path and is rate-determining for splicing at physiological temperatures is presented. Structural isomers were separated by native polyacrylamide gel electrophoresis and their splicing activities were compared. GTP binding selectivel...

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Autors principals: Emerick, V L, Woodson, S A
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC44879/
https://ncbi.nlm.nih.gov/pubmed/7937871
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