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Identification of Small-Molecule Scaffolds for P450 Inhibitors
Mycobacterium tuberculosis cytochrome P450 enzymes (P450, CYP) attract ongoing interest for their pharmacological development potential, as evidenced by the activity of antifungal azole drugs that inhibit sterol 14α-demethylase CYP51 in fungi, tightly bind M. tuberculosis CYP enzymes, and display in...
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| Publicado no: | Curr Protoc Microbiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4487866/ https://ncbi.nlm.nih.gov/pubmed/20131225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780471729259.mc1704s16 |
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