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Efficacy of B-Type Natriuretic Peptide Is Coupled to Phosphodiesterase 2A in Cardiac Sympathetic Neurons

Elevated B-type natriuretic peptide (BNP) regulates cGMP-phosphodiesterase activity. Its elevation is regarded as an early compensatory response to cardiac failure where it can facilitate sympathovagal balance and cardiorenal homeostasis. However, recent reports suggest a paradoxical proadrenergic a...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Li, Dan, Lu, Chieh-Ju, Hao, Guoliang, Wright, Hannah, Woodward, Lavinia, Liu, Kun, Vergari, Elisa, Surdo, Nicoletta C., Herring, Neil, Zaccolo, Manuela, Paterson, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487831/
https://ncbi.nlm.nih.gov/pubmed/25916722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.05054
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