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Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat

Hypertension is associated with heightened cardiac sympathetic drive whilst statins reduce angiotensin II (ATII) signalling, superoxide anion production and increase nitric oxide bioavailability, events that can potentially reduce peripheral cardiac sympathetic neurotransmission. We therefore invest...

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Detalhes bibliográficos
Main Authors: Herring, Neil, Lee, Chee Wan, Sunderland, Nicholas, Wright, Kathryn, Paterson, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020274/
https://ncbi.nlm.nih.gov/pubmed/20933519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.09.025
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