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l-arginine supplementation reduces cardiac noradrenergic neurotransmission in spontaneously hypertensive rats

Spontaneously hypertensive rats (SHR) are known to have cardiac noradrenergic hyperactivity due to an impaired nitric oxide (NO)–cGMP pathway. We hypothesized that dietary l-arginine supplementation may correct this autonomic phenotype. Male SHR and Wistar Kyoto rats (WKY) aged 16–18 weeks were give...

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Detalhes bibliográficos
Main Authors: Lee, Chee-Wan, Li, Dan, Channon, Keith M., Paterson, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734311/
https://ncbi.nlm.nih.gov/pubmed/19362092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.03.023
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