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An efficiency analysis of high-order combinations of gene–gene interactions using multifactor-dimensionality reduction

BACKGROUND: Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of genes to determine the complex relationship between diseases and polymorphisms in humans. However, the astronomical number of high-order combinations makes MDR a highly time-consuming process which can b...

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Vydáno v:BMC Genomics
Hlavní autoři: Yang, Cheng-Hong, Lin, Yu-Da, Yang, Cheng-San, Chuang, Li-Yeh
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487567/
https://ncbi.nlm.nih.gov/pubmed/26126977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1717-8
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