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Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction
BACKGROUND: Multifactor Dimensionality Reduction (MDR) has been widely applied to detect gene-gene (GxG) interactions associated with complex diseases. Existing MDR methods summarize disease risk by a dichotomous predisposing model (high-risk/low-risk) from one optimal GxG interaction, which does no...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560267/ https://ncbi.nlm.nih.gov/pubmed/23294634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-6-1 |
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