Global tests of P-values for multifactor dimensionality reduction models in selection of optimal number of target genes

BACKGROUND: Multifactor Dimensionality Reduction (MDR) is a popular and successful data mining method developed to characterize and detect nonlinear complex gene-gene interactions (epistasis) that are associated with disease susceptibility. Because MDR uses a combinatorial search strategy to detect...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Dai, Hongying, Bhandary, Madhusudan, Becker, Mara, Leeder, J Steven, Gaedigk, Roger, Motsinger-Reif, Alison A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Methodology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508622/
https://ncbi.nlm.nih.gov/pubmed/22616673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-5-3
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