Intravenous Cobinamide Versus Hydroxocobalamin for Acute Treatment of Severe Cyanide Poisoning in a Swine (Sus scrofa) Model

STUDY OBJECTIVE: Hydroxocobalamin is a Food and Drug Administration–approved antidote for cyanide poisoning. Cobinamide is a potential antidote that contains 2 cyanide-binding sites. To our knowledge, no study has directly compared hydroxocobalamin with cobinamide in a severe, cyanide-toxic large-an...

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Pubblicato in:Ann Emerg Med
Autori principali: Bebarta, Lt Col Vikhyat S., Tanen, David A., Boudreau, Susan, Castaneda, Maria, Zarzabal, Lee A., Vargas, Toni, Boss, Gerry R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487531/
https://ncbi.nlm.nih.gov/pubmed/24746273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annemergmed.2014.02.009
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