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Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring

Our purpose is to compare cobinamide to hydroxocobalamin in reversing cyanide (CN)–induced physiologic effects in an animal model using diffuse optical spectroscopy (DOS). Cyanide poisoning is a major threat worldwide. Cobinamide is a novel molecule that can bind two molecules of cyanide, has a much...

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Hlavní autoři: Brenner, Matthew, Mahon, Sari B., Lee, Jangwoen, Kim, Jae, Mukai, David, Goodman, Seth, Kreuter, Kelly A., Ahdout, Rebecca, Mohammad, Othman, Sharma, Vijay S., Blackledge, William, Boss, Gerry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society of Photo-Optical Instrumentation Engineers 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816993/
https://ncbi.nlm.nih.gov/pubmed/20210475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3290816
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