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Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring

Our purpose is to compare cobinamide to hydroxocobalamin in reversing cyanide (CN)–induced physiologic effects in an animal model using diffuse optical spectroscopy (DOS). Cyanide poisoning is a major threat worldwide. Cobinamide is a novel molecule that can bind two molecules of cyanide, has a much...

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Autors principals: Brenner, Matthew, Mahon, Sari B., Lee, Jangwoen, Kim, Jae, Mukai, David, Goodman, Seth, Kreuter, Kelly A., Ahdout, Rebecca, Mohammad, Othman, Sharma, Vijay S., Blackledge, William, Boss, Gerry R.
Format: Artigo
Idioma:Inglês
Publicat: Society of Photo-Optical Instrumentation Engineers 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816993/
https://ncbi.nlm.nih.gov/pubmed/20210475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3290816
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