Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring

Our purpose is to compare cobinamide to hydroxocobalamin in reversing cyanide (CN)–induced physiologic effects in an animal model using diffuse optical spectroscopy (DOS). Cyanide poisoning is a major threat worldwide. Cobinamide is a novel molecule that can bind two molecules of cyanide, has a much...

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Main Authors: Brenner, Matthew, Mahon, Sari B., Lee, Jangwoen, Kim, Jae, Mukai, David, Goodman, Seth, Kreuter, Kelly A., Ahdout, Rebecca, Mohammad, Othman, Sharma, Vijay S., Blackledge, William, Boss, Gerry R.
Format: Artigo
Sprog:Inglês
Udgivet: Society of Photo-Optical Instrumentation Engineers 2010
Fag:
Research Papers: Sensing
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816993/
https://ncbi.nlm.nih.gov/pubmed/20210475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3290816
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