HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study

OBJECTIVES: Tissue transglutaminase autoantibodies (tTGAs) represent the first evidence of celiac disease (CD) development. Associations of HLA-DR3-DQA1*05:01-DQB1*02:01 (i.e., DR3-DQ2) and, to a lesser extent, DR4-DQA1*03:01-DQB1*03:02 (i.e., DR4-DQ8) with the risk of CD differ by country, consiste...

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Publicat a:Am J Gastroenterol
Autors principals: Hadley, David, Hagopian, William, Liu, Edwin, She, Jin-Xiong, Simell, Olli, Akolkar, Beena, Ziegler, Anette-G., Rewers, Marian, Krischer, Jeffrey P., Chen, Wei-Min, Onengut-Gumuscu, Suna, Bugawan, Teodorica L., Rich, Stephen S., Erlich, Henry, Agardh, Daniel
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487515/
https://ncbi.nlm.nih.gov/pubmed/26010309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2015.150
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