OGG1 Involvement in High Glucose-Mediated Enhancement of Bupivacaine-Induced Oxidative DNA Damage in SH-SY5Y Cells

Hyperglycemia can inhibit expression of the 8-oxoG-DNA glycosylase (OGG1) which is one of the key repair enzymes for DNA oxidative damage. The effect of hyperglycemia on OGG1 expression in response to local anesthetics-induced DNA damage is unknown. This study was designed to determine whether high...

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Publicat a:Oxid Med Cell Longev
Autors principals: Liu, Zhong-Jie, Zhao, Wei, Zhang, Qing-Guo, Li, Le, Lai, Lu-Ying, Jiang, Shan, Xu, Shi-Yuan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486758/
https://ncbi.nlm.nih.gov/pubmed/26161242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/683197
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