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Topological events in single molecules of E. coli DNA confined in nanochannels

We present experimental data concerning potential topological events such as folds, internal backfolds, and/or knots within long molecules of double-stranded DNA when they are stretched by confinement in a nanochannel. Genomic DNA from E. coli was labeled near the ‘GCTCTTC’ sequence with a fluoresce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Analyst
Hauptverfasser: Reifenberger, Jeffrey G., Dorfman, Kevin D., Cao, Han
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486629/
https://ncbi.nlm.nih.gov/pubmed/25991508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an00343a
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