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Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension

Genome-wide association studies (GWAS) have prioritized a transcription factor, Nuclear Receptor 2 Family 2 (NR2F2), as being associated with essential hypertension in humans. Here we provide evidence that validates this association and indicates that Nr2f2 is a genetic determinant of blood pressure...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Kumarasamy, Sivarajan, Waghulde, Harshal, Gopalakrishnan, Kathirvel, Mell, Blair, Morgan, Eric, Joe, Bina
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486351/
https://ncbi.nlm.nih.gov/pubmed/25687237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7252
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