Isolation and high-throughput sequencing of two closely linked epistatic hypertension susceptibility loci with a panel of bicongenic strains

Interactions or epistasis between genetic factors may contribute to “missing heritability.” While linkage analyses detect epistasis, defining the limits of the interacting segments poses a significant challenge especially when the interactions are between loci in close proximity. The goal of the pre...

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Библиографические подробности
Главные авторы: Pillai, Resmi, Waghulde, Harshal, Nie, Ying, Gopalakrishnan, Kathirvel, Kumarasamy, Sivarajan, Farms, Phyllis, Garrett, Michael R., Atanur, Santosh S., Maratou, Klio, Aitman, Timothy J., Joe, Bina
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
Предметы:
Call for Papers: Updates on Mapping Quantitative Trait Loci
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3742915/
https://ncbi.nlm.nih.gov/pubmed/23757393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00077.2013
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