The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells

BACKGROUND: Phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway is a therapy target of cancer. We aimed to confirm the effect of dual PI3K/mTOR inhibitor NVP-BEZ235 on cell proliferation and apoptosis in Burkitt lymphoma (BL) cells. METHODS: Two human BL cell line...

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Detaylı Bibliyografya
Yayımlandı:Cancer Cell Int
Asıl Yazarlar: Li, Chuntuan, Xin, Pengliang, Xiao, Huifang, Zheng, Yan, Huang, Yuanling, Zhu, Xiongpeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Primary Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486138/
https://ncbi.nlm.nih.gov/pubmed/26130968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0213-1
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