Dose Escalation and Dosimetry of First in Human Alpha Radioimmunotherapy with (212)Pb-TCMC-trastuzumab

Our purpose was to study the safety, distribution, pharmacokinetics, immunogenicity and tumor response of intraperitoneal (IP) (212)Pb-TCMC-trastuzumab (TCMC is S-2-(4-isothiocyantobenzl)-1, 4, 7, 10-tetraaza-1, 4, 7, 10=tetra (2-carbamoylmethl) cyclododecane) in patients with HER-2 expressing malig...

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書目詳細資料
發表在:J Nucl Med
Main Authors: Meredith, Ruby, Torgue, Julien, Shen, Sui, Fisher, Darrell R., Banaga, Eileen, Bunch, Patty, Morgan, Desiree, Fan, Jinda, Straughn, J. Michael
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486012/
https://ncbi.nlm.nih.gov/pubmed/25157044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.143842
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