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The Nucleotide-Free State of the Multidrug Resistance ABC Transporter LmrA: Sulfhydryl Cross-Linking Supports a Constant Contact, Head-to-Tail Configuration of the Nucleotide-Binding Domains

ABC transporters are integral membrane pumps that are responsible for the import or export of a diverse range of molecules across cell membranes. ABC transporters have been implicated in many phenomena of medical importance, including cystic fibrosis and multidrug resistance in humans. The molecular...

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Publicado en:PLoS One
Main Authors: Jones, Peter M., George, Anthony M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485892/
https://ncbi.nlm.nih.gov/pubmed/26120849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131505
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