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Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8(+) T-cell responses and immune memory

Cancer chemotherapy using cytotoxic drugs can induce immunogenic tumor cell death; however, dosing regimens and schedules that enable single-agent chemotherapy to induce adaptive immune-dependent ablation of large, established tumors with activation of long-term immune memory have not been identifie...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Wu, Junjie, Waxman, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485826/
https://ncbi.nlm.nih.gov/pubmed/26137402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1005521
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