Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

Myeloid cells lacking STAT3 promote antitumor responses of NK and T cells but it is unknown if this crosstalk affects development of autochthonous tumors. We deleted STAT3 in murine myeloid cells (STAT3(Δm)) and examined the effect on the development of autochthonous colorectal cancers (CRCs). Forma...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Pathria, Paulina, Gotthardt, Dagmar, Prchal-Murphy, Michaela, Putz, Eva-Maria, Holcmann, Martin, Schlederer, Michaela, Grabner, Beatrice, Crncec, Ilija, Svinka, Jasmin, Musteanu, Monica, Hoffmann, Thomas, Filipits, Martin, Berger, Walter, Poli, Valeria, Kenner, Lukas, Bilban, Martin, Casanova, Emilio, Müller, Mathias, Strobl, Birgit, Bayer, Editha, Mohr, Thomas, Sexl, Veronika, Eferl, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485776/
https://ncbi.nlm.nih.gov/pubmed/26137415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.998529
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