Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model

Melanoma patients are at a high risk of developing brain metastases, which are strongly vascularized and therefore have a significant risk of spontaneous bleeding. VEGF not only plays a role in neo-angiogenesis but also in the antitumor immune response. VEGFR-targeted therapy might not only have an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Du Four, Stephanie, Maenhout, Sarah K., De Pierre, Kari, Renmans, Dries, Niclou, Simone P, Thielemans, Kris, Neyns, Bart, Aerts, Joeri L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485747/
https://ncbi.nlm.nih.gov/pubmed/26137411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.998107
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados