O1.05 AXITINIB, A SELECTIVE VEGFR-1,-2,-3 TYROSINE KINASE INHIBITOR, INHIBITS TUMOR GROWTH AND INCREASES INFILTRATION OF IMMUNE CELLS IN AN INTRACRANIAL MELANOMA MOUSE MODEL

VEGF is a key mediator of pathological cancer associated neoangiogenesis and immunosuppression. VEGFR targeted therapy holds promise to counteract cancer associated neoangiogenesis but also to alleviate cancer associated immune suppression. Melanoma patients are at high risk for developing brain met...

Full description

Saved in:
Bibliographic Details
Main Authors: Du Four, S., Maenhout, S.K., Niclou, S.P., Thielemans, K., Neyns, B., Aerts, J.L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
ORAL PRESENTATIONS
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185817/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items