HLA class I as a predictor of clinical prognosis and CTL infiltration as a predictor of chemosensitivity in ovarian cancer

Cytotoxic T lymphocytes (CTLs) recognize the human leukocyte antigen (HLA) class I and antigenic peptide complex, and they play a crucial role in cancer immunity. Our recent study revealed that HLA class I downregulation is related to poorer prognosis and a low level of intratumoral CTLs is associat...

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Publicado no:Oncoimmunology
Main Authors: Hirohashi, Yoshihiko, Torigoe, Toshihiko, Mariya, Tasuku, Kochin, Vitaly, Saito, Tsuyoshi, Sato, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485746/
https://ncbi.nlm.nih.gov/pubmed/26155404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1005507
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