Cargando...
CD39: A complementary target to immune checkpoints to counteract tumor-mediated immunosuppression
We report that CD39–expressing-melanoma cells inhibited both T-cell proliferation and the generation of cytotoxic effectors in an adenosine-dependent manner, and that treatment with a CD39-blocking antibody alleviated tumor-mediated immunosuppression. Thus, blocking CD39 ectonucleotidase may represe...
Gardado en:
| Publicado en: | Oncoimmunology |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485743/ https://ncbi.nlm.nih.gov/pubmed/26155397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.1003015 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|