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Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

Most studies on cellular senescence (CS) have been performed in vitro by employing cytotoxic agents, irradiation, chromatin and telomerase modulators or by activating certain oncogenes. All these approaches usually lead to DNA damage, gene instability and/or chromatin alterations that primarily affe...

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Dettagli Bibliografici
Pubblicato in:Int J Oncol
Autori principali: SHILKAITIS, ANNE, GREEN, ALBERT, CHRISTOV, KONSTANTIN
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485653/
https://ncbi.nlm.nih.gov/pubmed/25997921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3013
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