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Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

Most studies on cellular senescence (CS) have been performed in vitro by employing cytotoxic agents, irradiation, chromatin and telomerase modulators or by activating certain oncogenes. All these approaches usually lead to DNA damage, gene instability and/or chromatin alterations that primarily affe...

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Podrobná bibliografie
Vydáno v:Int J Oncol
Hlavní autoři: SHILKAITIS, ANNE, GREEN, ALBERT, CHRISTOV, KONSTANTIN
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485653/
https://ncbi.nlm.nih.gov/pubmed/25997921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3013
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