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Separating Chemical and Excluded Volume Interactions of Polyethylene Glycols with Native Proteins: Comparison with PEG Effects on DNA Helix Formation

Small and large PEGs greatly increase chemical potentials of globular proteins (μ(2)), thereby favoring precipitation, crystallization, and protein-protein interactions that reduce water-accessible protein surface and/or protein-PEG excluded volume. To determine individual contributions of PEG-prote...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Shkel, Irina A., Knowles, Ben, Record, M. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485569/
https://ncbi.nlm.nih.gov/pubmed/25924886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22662
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