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Supercharged green fluorescent proteins as bimodal reporter genes for CEST MRI and optical imaging
Superpositively charged mutants of green fluorescent protein (GFP) demonstrated a dramatically improved chemical exchange saturation transfer (CEST) MRI contrast compared to their wild type counterparts. The mutants +36 GFP and +48 GFP were successfully expressed in mammalian cells and retained part...
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Publicado no: | Chem Commun (Camb) |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485562/ https://ncbi.nlm.nih.gov/pubmed/25697683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc10195b |
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