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Glycogen Synthase Kinase-3 in Insulin and Wnt Signalling : a Double-edged Sword?
Glycogen synthase kinase-3 is an unusual protein-serine/threonine kinase that, unlike most of its 500-odd relatives in the genome, is active under resting conditions and is inactivated upon cell stimulation. The two mammalian isoforms, GSK-3α and β, play largely overlapping roles and have been impli...
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| Publicado no: | Biochem Soc Trans |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485494/ https://ncbi.nlm.nih.gov/pubmed/15494020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0320803 |
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