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Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

Ghrelin, a stomach-derived orexigenic peptide, transmits starvation signals to the hypothalamus via the vagus afferent nerve. Peripheral administration of ghrelin does not induce food intake in high fat diet (HFD)-induced obese mice. We investigated whether this ghrelin resistance was caused by dysf...

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Podrobná bibliografie
Vydáno v:J Endocrinol
Hlavní autoři: Naznin, Farhana, Toshinai, Koji, Waise, T M Zaved, NamKoong, Cherl, Md Moin, Abu Saleh, Sakoda, Hideyuki, Nakazato, Masamitsu
Médium: Artigo
Jazyk:Inglês
Vydáno: Bioscientifica Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485401/
https://ncbi.nlm.nih.gov/pubmed/26016745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-15-0139
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