Single-molecule analysis reveals widespread structural variation in multiple myeloma

Multiple myeloma (MM), a malignancy of plasma cells, is characterized by widespread genomic heterogeneity and, consequently, differences in disease progression and drug response. Although recent large-scale sequencing studies have greatly improved our understanding of MM genomes, our knowledge about...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gupta, Aditya, Place, Michael, Goldstein, Steven, Sarkar, Deepayan, Zhou, Shiguo, Potamousis, Konstantinos, Kim, Jaehyup, Flanagan, Claire, Li, Yang, Newton, Michael A., Callander, Natalie S., Hematti, Peiman, Bresnick, Emery H., Ma, Jian, Asimakopoulos, Fotis, Schwartz, David C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485118/
https://ncbi.nlm.nih.gov/pubmed/26056298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418577112
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