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Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

To study the multistep process of cervical cancer development, we analyzed 128 frozen cervical samples spanning normalcy, increasingly severe cervical intraepithelial neoplasia (CIN1– CIN3), and cervical cancer (CxCa) from multiple perspectives, revealing a cascade of progressive changes. Compared w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: den Boon, Johan A., Pyeon, Dohun, Wang, Sophia S., Horswill, Mark, Schiffman, Mark, Sherman, Mark, Zuna, Rosemary E., Wang, Zhishi, Hewitt, Stephen M., Pearson, Rachel, Schott, Meghan, Chung, Lisa, He, Qiuling, Lambert, Paul, Walker, Joan, Newton, Michael A., Wentzensen, Nicolas, Ahlquist, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485108/
https://ncbi.nlm.nih.gov/pubmed/26056290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509322112
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