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Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

To study the multistep process of cervical cancer development, we analyzed 128 frozen cervical samples spanning normalcy, increasingly severe cervical intraepithelial neoplasia (CIN1– CIN3), and cervical cancer (CxCa) from multiple perspectives, revealing a cascade of progressive changes. Compared w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: den Boon, Johan A., Pyeon, Dohun, Wang, Sophia S., Horswill, Mark, Schiffman, Mark, Sherman, Mark, Zuna, Rosemary E., Wang, Zhishi, Hewitt, Stephen M., Pearson, Rachel, Schott, Meghan, Chung, Lisa, He, Qiuling, Lambert, Paul, Walker, Joan, Newton, Michael A., Wentzensen, Nicolas, Ahlquist, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485108/
https://ncbi.nlm.nih.gov/pubmed/26056290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509322112
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