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Increased systemic and plaque inflammation in ABCA1 mutation carriers with attenuation by statins
OBJECTIVE: We previously demonstrated that subjects with functional ATP-binding cassette (ABC) A1 mutations have increased atherosclerosis, which has been attributed to the role of ABCA1 in reverse cholesterol transport. More recently, a pro-inflammatory effect of Abca1 deficiency was shown in mice,...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4484788/ https://ncbi.nlm.nih.gov/pubmed/26109739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304959 |
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