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Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies

INTRODUCTION: The thyroid-stimulating hormone receptor (TSHR) is the essential molecule for thyroid growth and thyroid hormone production. Since it is also a key autoantigen in Graves’ disease and is involved in thyroid cancer pathophysiology, the targeting of the TSHR offers a logical model for dis...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Main Authors: Davies, Terry F, Latif, Rauf
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484771/
https://ncbi.nlm.nih.gov/pubmed/25768836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2015.1018181
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