The Genetics of the Thyroid Stimulating Hormone Receptor: History and Relevance

BACKGROUND: The thyroid stimulating hormone receptor (TSHR) is the key regulator of thyrocyte function. The gene for the TSHR on chromosome 14q31 has been implicated as coding for the major autoantigen in the autoimmune hyperthyroidism of Graves' disease (GD) to which T cells and autoantibodies...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Davies, Terry F., Yin, Xiaoming, Latif, Rauf
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2010
Sujets:
Original Studies, Reviews, and Scholarly Dialog Special Section: Thyroid Disease in the Era of Personalized Medicine Guest Editors: Yaron Tomer, Virginia Sarapura, and George J. Kahaly
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935345/
https://ncbi.nlm.nih.gov/pubmed/20578897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.1638
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