The Genetics of the Thyroid Stimulating Hormone Receptor: History and Relevance

BACKGROUND: The thyroid stimulating hormone receptor (TSHR) is the key regulator of thyrocyte function. The gene for the TSHR on chromosome 14q31 has been implicated as coding for the major autoantigen in the autoimmune hyperthyroidism of Graves' disease (GD) to which T cells and autoantibodies...

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Detalhes bibliográficos
Main Authors: Davies, Terry F., Yin, Xiaoming, Latif, Rauf
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Original Studies, Reviews, and Scholarly Dialog Special Section: Thyroid Disease in the Era of Personalized Medicine Guest Editors: Yaron Tomer, Virginia Sarapura, and George J. Kahaly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935345/
https://ncbi.nlm.nih.gov/pubmed/20578897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.1638
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