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Conformational effects and stereocontrol in synthesis studies of medium-ring dolabellane carbocycles

Stereoselective reactions are described which lead to functionalization of the dolabellane skeleton. The stereoselectivity is attributed to conformational effects imposed by the eleven-membered ring. An efficient pathway provides for the stereocontrolled synthesis of nonracemic 6(S)-hydroxy-4(E)-dol...

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Williams, David R., Robinson, Leslie A., Bawel, Seth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484730/
https://ncbi.nlm.nih.gov/pubmed/26139943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.12.049
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