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Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials

BACKGROUND: The activity of several well-known anti-malarials, including chloroquine (CQ), is attributed to their ability to inhibit the formation of haemozoin (Hz) in the malaria parasite. The formation of inert Hz, or malaria pigment, from toxic haem acquired from the host red blood cell of the pa...

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Bibliografiska uppgifter
I publikationen:Malar J
Huvudupphovsmän: Combrinck, Jill M., Fong, Kim Y., Gibhard, Liezl, Smith, Peter J., Wright, David W., Egan, Timothy J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484700/
https://ncbi.nlm.nih.gov/pubmed/26099266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0729-9
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