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Impaired NFAT and NFκB Activation are Involved in Suppression of CD40 Ligand Expression by Δ(9)-Tetrahydrocannabinol in Human CD4(+) T cells
We have previously reported that Δ(9)-tetrahydrocannabinol (Δ(9)-THC), the main psychoactive cannabinoid in marijuana, suppresses CD40 ligand (CD40L) expression by activated mouse CD4(+) T cells. CD40L is involved in pathogenesis of many autoimmune and inflammatory diseases. In the present study, we...
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| Publicat a: | Toxicol Appl Pharmacol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4484623/ https://ncbi.nlm.nih.gov/pubmed/23999542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.08.023 |
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