Overexpression of the Cytosolic Form of Phosphoenolpyruvate Carboxykinase (GTP) in Skeletal Muscle Repatterns Energy Metabolism in the Mouse()

Transgenic mice, containing a chimeric gene in which the cDNA for phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C) (EC 4.1.1.32) was linked to the α-skeletal actin gene promoter, express PEPCK-C in skeletal muscle (1–3 units/g). Breeding two founder lines together produced mice with an activity of...

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Udgivet i:J Biol Chem
Main Authors: Hakimi, Parvin, Yang, Jianqi, Casadesus, Gemma, Massillon, Duna, Tolentino-Silva, Fatima, Nye, Colleen K., Cabrera, Marco E., Hagen, David R., Utter, Christopher B., Baghdy, Yacoub, Johnson, David H., Wilson, David L., Kirwan, John P., Kalhan, Satish C., Hanson, Richard W.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484620/
https://ncbi.nlm.nih.gov/pubmed/17716967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706127200
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