Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data

Apart from genetic mutations, epigenetic alteration is a common phenomenon that contributes to neoplastic transformation in colorectal cancer. Transcriptional silencing of tumor-suppressor genes without changes in the DNA sequence is explained by the existence of promoter hypermethylation. To test t...

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Udgivet i:Oncol Rep
Main Authors: KOK-SIN, TEOW, MOKHTAR, NORFILZA MOHD, HASSAN, NUR ZARINA ALI, SAGAP, ISMAIL, ROSE, ISA MOHAMED, HARUN, ROSLAN, JAMAL, RAHMAN
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484611/
https://ncbi.nlm.nih.gov/pubmed/25997610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.3993
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