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Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

The skin and mucous membranes are the anatomical sites were most viruses are first encountered by the immune system. Previous experiments have suggested that striated muscle cells are unique among mammalian cell types in their capacity to take up and express free DNA in the absence of a viral vector...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Raz, E, Carson, D A, Parker, S E, Parr, T B, Abai, A M, Aichinger, G, Gromkowski, S H, Singh, M, Lew, D, Yankauckas, M A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44844/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9519
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