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Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

The skin and mucous membranes are the anatomical sites were most viruses are first encountered by the immune system. Previous experiments have suggested that striated muscle cells are unique among mammalian cell types in their capacity to take up and express free DNA in the absence of a viral vector...

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Guardat en:
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Raz, E, Carson, D A, Parker, S E, Parr, T B, Abai, A M, Aichinger, G, Gromkowski, S H, Singh, M, Lew, D, Yankauckas, M A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44844/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9519
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