Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation

PURPOSE. The Fat family of atypical cadherins, originally identified in Drosophila, play diverse roles during embryogenesis and adult tissue maintenance. Among four mammalian members, Fat1 is essential for kidney and muscle organization, and is also essential for eye development; Fat1 knockout cause...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Sugiyama, Yuki, Shelley, Elizabeth J., Badouel, Caroline, McNeill, Helen, McAvoy, John W.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2015
Fag:
Lens
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484397/
https://ncbi.nlm.nih.gov/pubmed/26114487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17008
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