Impact of 3’UTR genetic variants in PCSK9 and LDLR genes on plasma lipid traits and response to atorvastatin in Brazilian subjects: a pilot study

Background: Hypercholesterolemia is a complex trait, resulting from a genetic interaction with lifestyle habits. Polymorphisms are a major source of genetic heterogeneity, and variations in 2 key cholesterol homeostasis genes; low-density lipoprotein receptor (LDLR) and proprotein convertase subtili...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Zambrano, Tomás, Hirata, Mario Hiroyuki, Cerda, Álvaro, Dorea, Egidio L, Pinto, Gelba A, Gusukuma, Maria C, Bertolami, Marcelo C, Salazar, Luis A, Hirata, Rosario Dominguez Crespo
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483840/
https://ncbi.nlm.nih.gov/pubmed/26131194
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